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NHTSA FARS 2020–2024

Deadliest Highways and Roads in South Carolina

Quick answer: US-17 is the deadliest road in South Carolina: 246 people died in crashes on it from 2020 to 2024, the worst stretch being near Horry County (18 deaths within about 7 miles). Next: I-26 (172) and I-95 (119).

#RoadDeathsFatal crashes2020 · 2024Deadliest ~7-mile stretchCounties
1 US-17
U.S. Highway
246221 47 → 44 near Horry County: 18 deaths map Horry County, Charleston County, Berkeley County, Georgetown County
2 I-26
Interstate
172146 38 → 33 near Lexington County: 13 deaths map Orangeburg County, Spartanburg County, Lexington County, Charleston County
3 I-95
Interstate · live page
119106 21 → 15 near Colleton County: 12 deaths map Colleton County, Dillon County, Clarendon County, Jasper County
4 US-52
U.S. Highway
10598 17 → 23 near Charleston County: 17 deaths map Berkeley County, Charleston County, Florence County, Williamsburg County
5 US-76
U.S. Highway
102100 18 → 17 near Anderson County: 8 deaths map Richland County, Anderson County, Sumter County, Florence County
6 US-21
U.S. Highway
9681 17 → 27 near Beaufort County: 14 deaths map Beaufort County, Orangeburg County, York County, Richland County
7 SR-9
State Highway
9385 21 → 24 near Spartanburg County: 7 deaths map Horry County, Spartanburg County, Lancaster County, Chesterfield County
8 I-20
Interstate
8980 20 → 18 near Richland County: 11 deaths map Richland County, Aiken County, Kershaw County, Lexington County
9 I-77
Interstate
8879 14 → 17 near Richland County: 10 deaths map Richland County, Chester County, York County, Fairfield County
10 US-29
U.S. Highway
8780 13 → 14 near Greenville County: 19 deaths map Spartanburg County, Greenville County, Anderson County, Cherokee County
11 US-25
U.S. Highway
8782 18 → 15 near Greenville County: 15 deaths map Greenville County, Greenwood County, Edgefield County, Aiken County
12 I-85
Interstate
7665 15 → 16 near Spartanburg County: 15 deaths map Spartanburg County, Greenville County, Cherokee County, Anderson County
13 US-1
U.S. Highway
7467 19 → 9 near Richland County: 14 deaths map Richland County, Lexington County, Aiken County, Kershaw County
14 US-176
U.S. Highway
7270 13 → 11 near Richland County: 10 deaths map Spartanburg County, Richland County, Berkeley County, Union County
15 US-378
U.S. Highway
5748 16 → 8 near Florence County: 6 deaths map Sumter County, Florence County, Lexington County, Marion County
16 US-15
U.S. Highway
5654 10 → 11 near Dorchester County: 7 deaths map Sumter County, Darlington County, Dorchester County, Colleton County
17 US-278
U.S. Highway
5448 19 → 10 near Beaufort County: 9 deaths map Beaufort County, Aiken County, Allendale County, Jasper County
18 US-301
U.S. Highway
5448 7 → 11 near Orangeburg County: 9 deaths map Orangeburg County, Dillon County, Florence County, Clarendon County
19 SR-34
State Highway
5250 14 → 6 near Greenwood County: 4 deaths map Newberry County, Kershaw County, Greenwood County, Lexington County
20 US-321
U.S. Highway
5250 15 → 14 near Fairfield County: 6 deaths map Orangeburg County, Fairfield County, Lexington County, Richland County
21 US-521
U.S. Highway
5145 8 → 8 near Lancaster County: 6 deaths map Lancaster County, Sumter County, Kershaw County, Clarendon County
22 US-501
U.S. Highway
5150 7 → 8 near Horry County: 17 deaths map Horry County, Marion County, Orangeburg County
23 SR-6
State Highway
5049 12 → 8 near Lexington County: 6 deaths map Lexington County, Berkeley County, Orangeburg County, Calhoun County
24 US-178
U.S. Highway
4943 8 → 9 near Orangeburg County: 5 deaths map Orangeburg County, Lexington County, Pickens County, Anderson County
25 US-221
U.S. Highway
4640 11 → 7 near Spartanburg County: 11 deaths map Spartanburg County, Cherokee County, Greenwood County, McCormick County
26 SR-20
State Highway
4241 15 → 5 near Greenville County: 7 deaths map Greenville County, Charleston County, Anderson County, Darlington County
27 SR-41
State Highway
3935 8 → 4 near Williamsburg County: 4 deaths map Marion County, Williamsburg County, Berkeley County, Colleton County
28 SR-28
State Highway
3835 5 → 8 near Anderson County: 9 deaths map Anderson County, McCormick County, Darlington County, Oconee County
29 SR-642
State Highway
3630 2 → 11 near Charleston County: 19 deaths map Charleston County, Dorchester County
30 SR-19
State Highway
3433 6 → 7 near Aiken County: 8 deaths map Aiken County, Horry County, Edgefield County, Dorchester County
31 I-385
Interstate
3327 7 → 8 near Greenville County: 10 deaths map Greenville County, Laurens County
32 SR-49
State Highway
3230 12 → 4 near York County: 3 deaths map York County, Union County, Laurens County, Darlington County
33 SR-72
State Highway
3228 4 → 6 near York County: 6 deaths map York County, Laurens County, Chester County, Abbeville County
34 US-601
U.S. Highway
3231 5 → 10 near Orangeburg County: 6 deaths map Hampton County, Richland County, Orangeburg County, Chesterfield County
35 US-78
U.S. Highway
3230 4 → 9 near Charleston County: 8 deaths map Charleston County, Dorchester County, Barnwell County, Aiken County
36 SR-31
State Highway
3127 8 → 2 near Horry County: 8 deaths map Horry County, Spartanburg County, Richland County, Lee County
37 SR-14
State Highway
3027 9 → 5 near Laurens County: 5 deaths map Greenville County, Laurens County, Spartanburg County, Darlington County
38 SR-81
State Highway
3026 6 → 5 near Anderson County: 6 deaths map Anderson County, Greenville County, Abbeville County, Aiken County
39 SR-61
State Highway
2726 6 → 4 near Charleston County: 9 deaths map Charleston County, Dorchester County, Colleton County, Cherokee County
40 US-123
U.S. Highway
2726 6 → 5 near Pickens County: 10 deaths map Pickens County, Greenville County, Oconee County
41 SR-291
State Highway
2726 6 → 7 near Greenville County: 13 deaths map Greenville County, Pickens County
42 SR-11
State Highway
2725 3 → 4 near Spartanburg County: 3 deaths map Oconee County, Spartanburg County, Pickens County, Greenville County
43 SR-62
State Highway
2625 4 → 2 near Berkeley County: 14 deaths map Berkeley County, Dorchester County, Spartanburg County, Greenville County
44 US-276
U.S. Highway
2524 3 → 7 near Greenville County: 10 deaths map Greenville County
45 SR-24
State Highway
2521 9 → 3 near Colleton County: 3 deaths map Oconee County, Anderson County, Colleton County, Florence County
46 US-701
U.S. Highway
2524 5 → 6 near Horry County: 7 deaths map Horry County, Georgetown County
47 SR-22
State Highway
2422 4 → 4 near Anderson County: 6 deaths map Anderson County, York County, Dorchester County, Horry County
48 SR-39
State Highway
2320 6 → 4 — Saluda County, Laurens County, Greenwood County, Dillon County
49 SR-51
State Highway
2320 2 → 3 near Georgetown County: 5 deaths map Georgetown County, Florence County, Sumter County, Lancaster County
50 SR-183
State Highway
2222 6 → 4 near Greenville County: 8 deaths map Greenville County, Pickens County, Oconee County
51 SR-48
State Highway
2221 5 → 2 near Richland County: 7 deaths map Richland County, Berkeley County, Kershaw County, Clarendon County
52 SR-53
State Highway
2218 5 → 2 near Charleston County: 6 deaths map Sumter County, Charleston County, Florence County, Laurens County
53 SR-215
State Highway
2116 3 → 4 near Spartanburg County: 7 deaths map Union County, Spartanburg County, Fairfield County, Richland County
54 SR-45
State Highway
2118 7 → 1 near Orangeburg County: 6 deaths map Orangeburg County, Colleton County, Berkeley County, Marion County
55 SR-38
State Highway
2121 7 → 0 near Dillon County: 3 deaths map Marlboro County, Dillon County, Georgetown County, Florence County
56 SR-162
State Highway
2020 6 → 6 near Charleston County: 7 deaths map Charleston County, York County, Dorchester County, Anderson County
57 SR-5
State Highway
2017 5 → 2 near York County: 5 deaths map York County, Greenville County, Cherokee County, Lancaster County
58 SR-13
State Highway
2018 4 → 0 near Charleston County: 8 deaths map Charleston County, Florence County, Oconee County, Darlington County
59 SR-29
State Highway
1919 6 → 2 near Berkeley County: 9 deaths map Berkeley County, Horry County, Chesterfield County, Laurens County
60 SR-12
State Highway
1918 3 → 3 near Richland County: 5 deaths map Richland County, Kershaw County, Florence County, Lancaster County

Deaths = people killed in crashes on the road, 2020–2024. A crash counts for the first signed Interstate, US or State route of its location; county and unsigned roads are not ranked because their numbers repeat. The stretch is the ~7-mile square with the most deaths on that road. Source: NHTSA FARS.

Questions

Deadliest roads — FAQ

What is the deadliest highway in South Carolina?
US-17 is the deadliest road in South Carolina: 246 people died in crashes on it from 2020 to 2024, the worst stretch being near Horry County (18 deaths within about 7 miles). Next: I-26 (172) and I-95 (119). Long, busy highways lead on totals; the deadliest-stretch column shows where on each road the deaths cluster.
Why is there no deaths-per-mile figure?
FARS records where each fatal crash happened but not how long each route is or how much traffic it carries, so we show totals and the worst ~7-mile stretch rather than a rate we would have to estimate.
Where does this data come from?
NHTSA's Fatality Analysis Reporting System, which records every fatal crash on US public roads, for 2020–2024. Each crash is credited to the first signed Interstate, US or State route of its trafficway.